Noise Contributions in an Inducible Genetic Switch: A Whole-Cell Simulation Study
Figure 8
Parameter fitting for inducer–repressor–operator interactions.
(A) Fraction of operator regions bound by a repressor as a function of time following an increase of IPTG to the indicated concentration. In these simulations, . (B) Number of bursts over the mean protein lifetime as a function of inducer concentration for a variety of values of the
parameter. x are data from Choi et al. [22].