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A Toolbox Model of Evolution of Metabolic Pathways on Networks of Arbitrary Topology

Figure 7

nbyproduct vs..

Faster-than-linear scaling of the number of byproducts, nbyproduct, and the total number of metabolites, , in individual branched pathways illustrated in Figure 4. Data for individual pathways were logarithmically binned along the x-axis. Hence y-axis can be and are below 1 due to pathways with 0 byproducts. The solid line with exponent 1.7+/−0.1 is the best fit to the logarithmically-binned data shown in this plot. Readers can refer to the section “Analysis of number of by-product of the pathways of the toolbox model on the metabolic network with branched pathways and multi-substrates reactions” of Text S1 for our estimation methods and error analysis.

Figure 7

doi: https://doi.org/10.1371/journal.pcbi.1001137.g007