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A Toolbox Model of Evolution of Metabolic Pathways on Networks of Arbitrary Topology

Figure 5

vs. of toolbox model with branched pathways and multi-substrate reactions.

The scaling between the number of regulated pathways (leaves), and the number of metabolites, , in metabolic networks generated by the toolbox model with branched pathways and multi-substrate reactions. Solid line with slope 2.0+/−0.1 is the best fit to the data. Error bars reflect the standard deviation of at a given value of in 9 realizations of the model (see he section “Error analysis of the toolbox model” of Text S1 for our estimation methods and error analysis).

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1001137.g005