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A Toolbox Model of Evolution of Metabolic Pathways on Networks of Arbitrary Topology

Figure 2

vs. .

is the number of leaves in an organism-specific metabolic network and equal to the number of transcriptional regulators of corresponding nutrient-utilizing pathways, while is the total number of nodes/metabolites in this netowrk. The data are generated by the toolbox model on critical universal network with sizes around 2000. Solid line , where the exponent and the prefactor , are the best fits to the binned data.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1001137.g002