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Causal Modeling Using Network Ensemble Simulations of Genetic and Gene Expression Data Predicts Genes Involved in Rheumatoid Arthritis

Figure 2

Consensus topology of network ensembles for pre-treated and TNF-α blocker treated data.

A. Snapshot of the network ensemble at 2.5% consensus topology generated from pre-treated subjects. Pain does not appear to be controlled by measures extracted from whole blood mRNA profiling in pre-treated subjects. B. Snapshot of the network consensus topology at 2.5% consensus generated from TNF-α blocker treated data.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1001105.g002