Identifying Causal Genes and Dysregulated Pathways in Complex Diseases
Figure 6
The network of causal paths from and to EGFR.
In (A) we show a network of causal paths that included EGFR as a causal gene. While this network was rather small, we found a large network of causal paths where EGFR was a target gene in (B). Specifically, we observed that EGFR might be influenced by numerous causal genes through prominent transcription factors.