< Back to Article

Identifying Causal Genes and Dysregulated Pathways in Complex Diseases

Figure 5

The network of causal paths from PTEN.

We observed that PTEN might exert its influence on target genes (the endpoints of each causal path) through prominent transcription factors such as TP53, MYC and MYB.

doi: https://doi.org/10.1371/journal.pcbi.1001095.g005