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A Hybrid Model of Mammalian Cell Cycle Regulation

Figure 4

Contact inhibition of a culture of human umbilical vein endothelial cells.

(A) Growth curve for the HUVEC population over 10 days, showing the base-10 logarithm of the cell count for both experimental data and our simulation (with N0 = 11000 and N1 = 500). (B) Daily distribution of cells across the phases of the cell cycle, from experimental data. (C) Model simulation of the phase distributions.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1001077.g004