Integrative Features of the Yeast Phosphoproteome and Protein–Protein Interaction Map
Figure 6
Number counts of interacting protein pairs of each phosphorylation pattern shown in the phospho-PPI network.
Respective rows of panels correspond to the three phosphorylation patterns of two interacting proteins: “Both” (A,B) “Either” (C,D) and “Neither” (E,F) respective columns correspond to PPI categories of “ALL” (A,C,E) and “Y2H” (B,D,F). In each panel, data are shown for two types of phospho-PPI networks: “whole” (i.e. unfiltered) and “filtered” (see text). Colored bars (purple, blue, and pink) represent number counts of protein interactions in real data sets; gray bars show mean values of those estimated by negative controls generated by random edge rewiring (N = 10,000). Error bars represent s.d. Blue/red asterisks denote significance of values higher/lower than those of negative controls (***P<0.001).