Modeling Mechanisms of In Vivo Variability in Methotrexate Accumulation and Folate Pathway Inhibition in Acute Lymphoblastic Leukemia Cells
Figure 5
MTXPG model parameters vs germline SNPs.
(A) VMAXFPGS vs FPGS SNP (DB SNP ID: rs1544105). (B) VMAXFPGS vs FPGS SNP (DB SNP ID: rs7033913). The p-values were determined by the Kruskal-Wallis ANOVA.