Modeling Mechanisms of In Vivo Variability in Methotrexate Accumulation and Folate Pathway Inhibition in Acute Lymphoblastic Leukemia Cells
Figure 4
MTXPG model parameters vs gene expression in ALL blasts at diagnosis.
(A) SLC19A1 expression (Probe Set ID: 209775_x_at) vs Influx. (B) SLC19A1 (Probe Set ID: 211576_s_at) vs NET-influx. (C) FPGS expression (Probe Set ID: 202945_at) vs NET-PG.