A New Method to Reconstruct Recombination Events at a Genomic Scale
Figure 7
Sensitivity of the optimal method evaluated in silico.
The plot shows the number of times in silico recombination events along the sequence were detected by IRiS depending on the breakpoint location. Different colors indicate different ways to produce the recombinant sequence, from light gray to black: “random” indicates that parental haplotypes were taken at random, “1dif near bkp” indicates that parental sequences had to be different near the breakpoint region (plus minus 10 SNPs), “ 2 dif near bkp” indicates that parental sequences had to be different near the breakpoint regions at both sides of the breakpoint, and “ unique” indicates that the parental sequences had to be different near the breakpoint region and the recombinant sequence had to be unique within the breakpoint region. Below, the recombination rate estimated by LDhat is shown, following the right axis.