Non-Centered Spike-Triggered Covariance Analysis Reveals Neurotrophin-3 as a Developmental Regulator of Receptive Field Properties of ON-OFF Retinal Ganglion Cells
Figure 5
NT-3 OE mice exhibit stronger STC-NC signal strength at P15 and at P18.
(A) Average cell count for NT-3 OE and WT controls at the three ages analyzed by the STC-NC or the STA method. (B) Plot of the STC-NC or the STA signal strength in s.d. against mouse age for WT and NT-3 OE mice. (C–D) Immunostainings with Brn-3a and SMI-32 antibodies demonstrated that WT and NT-3 OE retinas did not differ in total RGC number or cell body size at P16. Error bars represent S.E.M. throughout. ***: p<0.001; **: p<0.01; *: p<0.05 in Student's t-test.