Bistability in Apoptosis by Receptor Clustering
Figure 7
Sensitivity analysis of bistability thresholds.
The robustness of the bistability thresholds is investigated by measuring the effects of perturbating the model parameters about baseline values. For each threshold-parameter pair, a normalized sensitivity is computed by linear regression. Top, sensitivities for the FasL thresholds
; bottom, sensitivities for the corresponding Fas thresholds
at FasL concentrations
, respectively.