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Bistability in Apoptosis by Receptor Clustering

Figure 5

Steady state diagram.

Steady state diagram identifying the regions of parameter space supporting monostability (colored) or bistability (gray) as a function of the FasL and total Fas concentrations and , respectively. The monostable region is colored as a heat map corresponding to the steady-state active Fas concentration . Irreversible bistability is indicated by the extension of the bistable region to the axis .

doi: https://doi.org/10.1371/journal.pcbi.1000956.g005