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Bistability in Apoptosis by Receptor Clustering

Figure 4

Steady-state activation surface.

The steady-state surface for the active Fas concentration as a function of the FasL and total Fas concentrations and , respectively, is folded, indicating the existence of singularities, across which the system's steady-state behavior switches between monostability and bistability (stable, blue; unstable, red). All parameters set at baseline values unless otherwise noted.

doi: https://doi.org/10.1371/journal.pcbi.1000956.g004