Systems Biology of Coagulation Initiation: Kinetics of Thrombin Generation in Resting and Activated Human Blood
Figure 4
Coagulation initiation in the absence of externally added TF.
Blood drawn into 50 µg/ml CTI and without added TF, will still reproducibly clot in ∼75 minutes. Prior activation of platelets with CVX will lower initiation time to ∼20 minutes. Shown are the multiple replicates tested under the same conditions with the same phlebotomy.