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Finding the “Dark Matter” in Human and Yeast Protein Network Prediction and Modelling

Figure 4

PG networks functional context validation by the KG≥2 evidences dataset.

These plots present the precision value (y-axis) versus specific bits similarity score between the interaction profiles of the protein pairs (x-axis in plots A and C) and versus Recall (# of pairs predicted, x-axis in plots B and D) in yeast (plots A and B) and human (plots C and D) PG 0.001&0.0014 networks. The gold standard dataset used, KG≥2 evidences, is described in the section: Validation of the second order predictions for the PG networks.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1000945.g004