Thermodynamics-Based Models of Transcriptional Regulation by Enhancers: The Roles of Synergistic Activation, Cooperative Binding and Short-Range Repression
Figure 3
The predicted expression profile of the DirectInt model (with Bcd and Kni self-cooperativity) is shown (blue) in comparison to the known readout (red), for all CRMs in the data set. Each expression profile is on a scale of 0 to 1 (y-axis), and shown for bins 20 (left) to 80 (right) of the embryo. Labels in green indicate CRMs where the CC is greater than 0.65.