Drug-Induced Regulation of Target Expression
Figure 3
Drug-induced differentially regulated drug targets.
Anova is used to assess the significance of the differential expression of drug-induced drug targets against the mRNA changes of the same gene in the population of heterogeneous drug treatments from CMap. The genes are mainly ordered based on their q-values as provided in Table S1. In the scatter plots, inhibitors/activators are labeled in red/green respectively and grey represents all other treatments present in CMap.