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Reverse Engineering of Oxygen Transport in the Lung: Adaptation to Changing Demands and Resources through Space-Filling Networks

Figure 3

Computed and experimental oxygen currents and pulmonary efficiencies.

(A) Computed and experimental O2 currents for the whole lung and (B) pulmonary efficiencies, at different levels of exercise (levels of exercise are defined in the Methods section). The currents are computed from Eqs. 4 and 5. The computed pulmonary efficiency is obtained from Eqs. 5 and 7a, and the experimental value of the efficiency is obtained from Eq. 7c. In this figure, we compute the oxygen current with the physiological permeability, so instead of treating W as a variable, we take W = Wp (Table 1). Other transport parameters in the equations are listed in Table 1. The structural parameters at different levels of exercise are listed in Table 2 (column 2, 3, 4, and 5). The fractal dimension, Df, is taken to be 3.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1000902.g003