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More Than 1,001 Problems with Protein Domain Databases: Transmembrane Regions, Signal Peptides and the Issue of Sequence Homology

Figure 7

Histograms of average log probability per predicted transmembrane helix for SCOP v1.75 α-proteins class and membrane protein class.

The top (average log probability per predicted transmembrane helix for SCOP v1.75 α-proteins class) and bottom (average log probability per predicted transmembrane helix for SCOP v1.75 membrane protein class) histograms represent the false-positive and true-positive distributions for TM predictions respectively. The total number of predicted structural and membrane helices is 2293 and 5592 respectively.

Figure 7

doi: https://doi.org/10.1371/journal.pcbi.1000867.g007