< Back to Article

Patterns of HIV-1 Protein Interaction Identify Perturbed Host-Cellular Subsystems

Figure 3

Venn diagrams showing biological cohesiveness among proteins within significant biclusters, using three measures.

Counts refer to the number of biclusters that include human proteins that are significantly biologically related () from a possible 279. (A) Displays three network clustering measures: shared edge count, average shortest path and largest connected component. (B) Displays semantic similarity in terms of the three GO ontologies. (C) Displays the overlap of all three measures of biological cohesiveness: semantic similarity, network clustering and sequence similarity.

doi: https://doi.org/10.1371/journal.pcbi.1000863.g003