G-Quadruplex DNA Sequences Are Evolutionarily Conserved and Associated with Distinct Genomic Features in Saccharomyces cerevisiae
Figure 5
The distribution of G4 DNA motifs across the S. cerevisiae mitochondrial DNA.
The horizontal black line represents the 75kb mtDNA genome. The rectangles above mark the location of tRNA genes (green), rRNA genes (red), and ORFs (blue). ORFs that encode multiple genes (like COX1, subunit I of cytochrome c oxidase) are drawn as a single rectangle. The vertical black lines below indicate the location of the 32 G4 DNA motifs across the mtDNA. The width of these lines reflects the actual length of the G4 DNA motif. (Note that several motifs are so close that they overlap in the figure.) All motifs are drawn below the mtDNA sequence regardless of the strand on which they occur. The distribution of mitochondiral G4 DNA motifs is biased against overlapping these genomic features; only two of the 32 motifs overlap a tRNA, rRNA, or ORF (q<0.001).