Learning a Weighted Sequence Model of the Nucleosome Core and Linker Yields More Accurate Predictions in Saccharomyces cerevisiae and Homo sapiens

doi:10.1371/journal.pcbi.1000834

Learning a Weighted Sequence Model of the Nucleosome Core and Linker Yields More Accurate Predictions in Saccharomyces cerevisiae and Homo sapiens

Figure 2

X-ray structure of the nucleosome core particle.

These views of NCP147, at Å resolution, show the two strands of the double-helix in purple and green, with the protein core in grey. (A) shows the curvature of DNA around the histone core, with the dyad at the top, center; (B) represents a rotation of the particle, showing the adjacent segments of DNA, opposite the dyad; and (C) represents a rotation in the opposite direction, showing the DNA crossing over the dyad. As indicated by the coordinate system axes, in (A) the y-axis is pointing out of the page, in (B) the z-axis is pointing into the page, and in (C) the z-axis is pointing out of the page.

doi: https://doi.org/10.1371/journal.pcbi.1000834.g002