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Plato's Cave Algorithm: Inferring Functional Signaling Networks from Early Gene Expression Shadows

Figure 2

PLACA methodology overview.

The flow chart describes the methodology proposed in Plato's Cave Algorithm. The algorithm is made of three stages: Data acquisition; Reverse Engineering that is repeated several times for statistical significance; and Post-processing where the results of several experiments are integrated.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1000828.g002