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Impact of Dendritic Size and Dendritic Topology on Burst Firing in Pyramidal Cells

Figure 10

Mean electrotonic path length correlates with the region of burst firing for trees whose segment diameters obey Rall's power law.

The degree of burst firing (color coded) is shown as a function of both dendritic topology and total dendritic length, under somatic stimulation (Left) and dendritic stimulation (Right). The superimposed white lines are contour lines of equal mean electrotonic path length (MEP, in units of the electrotonic length constant), showing all the combinations of dendritic length and dendritic topology that result in a given MEP value. Especially the onset of burst firing is strongly associated with mean electrotonic path length.

Figure 10

doi: https://doi.org/10.1371/journal.pcbi.1000781.g010