Spontaneous Quaternary and Tertiary T-R Transitions of Human Hemoglobin in Molecular Dynamics Simulation
Figure 8
Schematic representation of consensus transition pathways between the R and T state as derived from the MD simulations.
The large sphere and square depict the quaternary R and T states, respectively, whereas the small spheres and squares depict tertiary r and t states, respectively. A square with round corners indicates an intermediate structure between R and T or between r and t.