Ion Channel Density Regulates Switches between Regular and Fast Spiking in Soma but Not in Axons
Figure 2
Oscillation maps for the hippocampal neuron model.
(A) Regions in the −
plane associated with different threshold dynamics. Oscillations occur within the area defined by the continuous line. Double-limit cycle bifurcations in the A2 region, Andronov-Hopf bifurcations (together with double-limit cycle bifurcations) in the B region and saddle-node bifurcations in the C1 region. The bold dashed line indicates the border for channel densities associated with three stationary potentials. The map is a projection of a curved plane in the
−
−Istim space (on which the oscillation starts) to the
−
plane. (B) The corresponding three-dimensional map, showing the volume associated with oscillations in the
−
−Istim space. Oscillations occur in the volume defined by blue and green surfaces. The green surface area represents double-limit cycle bifurcations and the blue area saddle-node bifurcations (SNICs).