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A Multi-Variant, Viral Dynamic Model of Genotype 1 HCV to Assess the in vivo Evolution of Protease-Inhibitor Resistant Variants

Figure 8

Objective values for alternative equations representing enhanced infected-cell clearance rates δ (Equations 5, 6, and 7).

Each of the models have the same number of parameters estimated for each subject. Models with δi that depend on blockage ε (Equations 5 and 6) have similar quality of fits. However, the model without dependency to ε (Equation 7) has inferior quality of fits.

Figure 8

doi: https://doi.org/10.1371/journal.pcbi.1000745.g008