A Multiscale Model to Investigate Circadian Rhythmicity of Pacemaker Neurons in the Suprachiasmatic Nucleus
Figure 5
Effects of VIP on circadian rhythmicity.
Circadian profiles of firing rate (A) and Per mRNA (B) for the control (black line), VIP blockade (red dashed line) and VIP application (blue dotted line). C) % amplitude decrease in firing rate, Per mRNA and IPSCs as a result of VIP blockade. D) % amplitude increase in firing rate, Per mRNA and IPSCs as a result of VIP application.