A Multiscale Model to Investigate Circadian Rhythmicity of Pacemaker Neurons in the Suprachiasmatic Nucleus
Figure 2
Oscillatory profiles of individual cellular clocks.
Rhythmic profiles of the potassium (A), sodium (B), calcium (C), Ca2+-activated potassium (D), excitatory (E) and inhibitory (F) currents. Intracellular calcium (G), Per mRNA (H) and the firing rate (I) also displayed oscillations that peaked during the subjective day. The arrows in Fig. 2G denote CT 1.5, which is the time Cain peaks. The gray and black bars on the top of each figure represent the alternation between the subjective day (gray) and night (black) that compose a 24h circadian cycle in constant darkness.