Effects of Transcriptional Pausing on Gene Expression Dynamics
Figure 9
Effects of a sequence-specific long-duration pause.
Time interval between the completion of consecutive RNA molecules in a gene with 400 nucleotides in case (A) without long-duration pause sites, case (B) with one long-pause site at nucleotide 200 where kpause is half the value of the rate of stepwise elongation and dpause is 1 min, and case (C), identical to case (B) but with a 20% chance that a long-paused RNAP will lead to premature termination.