Stochastic Model of Integrin-Mediated Signaling and Adhesion Dynamics at the Leading Edges of Migrating Cells
Figure 3
Exploration of model parameter space by phase plane analysis.
The nullclines for n (green) and s (magenta) are plotted in (v, s) space. For the n-nullclines, the values of the ECM parameter are 0.03 (light green), 0.1 (green), and 0.3 (dark green) min−1. Intersections of the n- and s-nullclines are fixed points of the system. The values of Es and In are varied as indicated, and all other parameters are assigned base case values (Supplementary Table S1).