A Dynamic Model of Interactions of Ca2+, Calmodulin, and Catalytic Subunits of Ca2+/Calmodulin-Dependent Protein Kinase II
Figure 9
Differences in predicted autophosphorylation between Model 1, Model 2, and an Empirical Model, at varying concentrations of Ca2+ and reaction times.
A) Surface plot of ratio of autophosphorylation predicted by the Empirical model and by Model 1. B) Surface plot of ratio of autophosphorylation predicted by Model 2 and by Model 1. In A and B Contour lines for 1, 5, and 60 sec reaction times are shown in light gray. C) Ca2+-dependence of the ratio of autophosphorylation predicted by the Empirical model and Model 1 at 1, 5, and 60 sec reaction times. D) Same as C for ratio of autophosphorylation predicted by Model 2 and Model 1.