Human Cancer Protein-Protein Interaction Network: A Structural Perspective
Figure 10
Ribbon diagram and interface representation of RAF1 interactions with YWHAZ, MAP2K2 and CDC25A.
RAF1 (1c1y_B), YWHAZ (1qja_A), MAP2K2 (1s9i_A) and CDC25A (1c25_A) are colored in blue, red, cyan and purple respectively. (A) RAF1-YWHAZ interaction. (B) RAF1-MAP2K2 interaction. (C) RAF1-CDC25A interaction. Interaction interfaces of RAF1 through YWHAZ, MAP2K2 and CDC25A are highly overlapping; the interactions are mutually exclusive.