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A Model Analysis of Arterial Oxygen Desaturation during Apnea in Preterm Infants

Figure 10

Conceptual framework depicting the temporal sequence of influence of the key cardiorespiratory factors on .

Note the regions of influence of lung volume (), cardiac output () and blood volume (), each with respect to metabolic O2 consumption (). Hemoglobin content (Hb) influences the latter phase of stage 1 as well as stage 2. The impact of reduced is limited to stage 1, and blood volume to stage 2. Reduced causes a leftward shift in the desaturation trajectory. Note that the point of inflection at the transition between stages reveals the resting .

Figure 10

doi: https://doi.org/10.1371/journal.pcbi.1000588.g010