A Model Analysis of Arterial Oxygen Desaturation during Apnea in Preterm Infants
Figure 4
Impact of pre-apneic alveolar (ventilation, supplemental O2) on
.
(A) Effect of three levels of alveolar (
), (i) 100 mmHg, (ii) 80 mmHg and (iii) 60 mmHg, on arterial (
) and mixed venous (
) O2 desaturation during apnea. Note that arterial O2 desaturation is substantially right-shifted with increased
. (B) Sensitivity of
to changes in pre-apneic
(
). Note that reduced
has a major impact on
but little impact on
; the influence on
is small in the normal range but becomes stronger at low
. n = ‘normal’ 'values; S1, stage 1 slope; S2, stage 2 slope.