Statistical Use of Argonaute Expression and RISC Assembly in microRNA Target Identification
Figure 8
Estimated effects of marginal miR-29c expressions and miR-30d Ago 2 RISC proxies.
Distributions of miR-30d Ago 2 RISC proxy effects across all genes measured in the Madison dataset suggest two classes of genes – those with no relationship to miR-30d, and those negatively regulated by miR-30d. Analogous distributions of marginal miR-29c expression effects suggest no such dichotomy, and are negatively biased.