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Thermodynamic Selection of Steric Zipper Patterns in the Amyloid Cross-β Spine

Figure 6

Integrity of β-sheet bilayer patterns during the production run.

(A) Distance between β-sheets in a bilayer. (B) RMSD of Cα atoms from the first snapshot. Within the simulation time, no filament except for FBA2 dissociated. The distance between β-sheets was defined by the distance between the least-squares-fit plane spanned by Cα atoms in one layer and the center of mass of Cα atoms in the other layer.

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.1000492.g006