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Temporal Controls of the Asymmetric Cell Division Cycle in Caulobacter crescentus

Figure 4

Simulated variations of proteins and other model state variables during the swarmer wild-type cell cycle.

Simulation begins with initiation of DNA replication. Three cell cycles are shown. Experimental data presented on some panels by open circles and squares, crosses and asterisks are re-plotted from the following sources: (A) Total DNA from Figure 4 in [84]. (B) CcrM from Figure 2 in [85]. (C) FtsZ from Fig. 2C in [86]; Zring from Fig. 3C in [87]; FtsQ from figure 2 in [86]. (D) Z from Figure 2 in [88]. (E) CtrA from Fig. 3C in [40]; CtrA∼P from Fig. 3C in [36]; GcrA from Figure 3 in [40]; DnaA from Figure 5 in [89]. (F) PodJL/PleC from Fig. 1A in [55] and Fig. 1B in [34]; DivJ from Fig. 2B in [33]; PerP from Fig. 4 in [55]. (G) DivK∼P from Figure 2 in [85]. (H) CckA∼P from Fig. 3B in [36]; CpdR from Fig. 5A in [35]; RcdA from Fig. 2C in [38].

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1000463.g004