Modeling the Impact of Lesions in the Human Brain
Figure 4
Dynamic effects of lesions along the brain's midline.
(A) L194. (B) L821. In this plot, as well as in Figures 5, 6 and S1, a dorsal view of the brain (middle panel) and two lateral views of the left hemisphere (left panels) and the right hemisphere (right panels) are shown. The middle panel plots all significantly different functional connections, while the left and right panels only show significantly different functional connections within the left and right hemispheres, respectively. The 998 ROI z-score FC matrix was aggregated to 66 subregions, and pathways between these 66 subregions are plotted if at least 10% of their constituent connections linking ROI pairs are significantly changed (|z|>3.3) as a result of the lesion. Pathways are plotted in red or blue, if their coupling has been weakened or strengthened, respectively. The approximate lesion center is marked with a green “+”.