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FINDSITELHM: A Threading-Based Approach to Ligand Homology Modeling

Figure 12

Ligand binding pose prediction for glutathione S-transferase (PDB-ID: 1a0f).

Predicted poses (thick sticks) from FINDSITELHM (superimposed ligand with the anchor portion colored in white and minimized conformation), AutoDock, LIGIN, Q-Dock and a randomly placed ligand are compared to the experimental binding pose (thin sticks). RMSD values were calculated for heavy atoms.

Figure 12

doi: https://doi.org/10.1371/journal.pcbi.1000405.g012