FINDSITELHM: A Threading-Based Approach to Ligand Homology Modeling
Figure 7
Ligand anchor identification for the human MTA phosphorylase (PDB-ID: 1sd2; SCOP superfamily/family: Purine and uridine phosphorylases/Purine and uridine phosphorylases; EC: 2.4.2.28).
Common anchor substructure (A) identified from weakly homologous threading templates as well as different variable groups (at the positions R1–R7) found in ligands complexed with the template proteins are presented.