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SpaK/SpaR Two-component System Characterized by a Structure-driven Domain-fusion Method and in Vitro Phosphorylation Studies

Figure 3

Homology model of a SpaK-SpaR complex.

A: Model is based on the A and E chains of SPO0B, a phosphotransferase, complexed with SPO0F, a beryllofluoride (PDB template 2ftk). Blue, red: monomers of SpaK; Green: SpaR. B: Close up view of interacting residues (SpaK: H247; SpaR: D8, D9, D51; shown as stick) believed to mediate transfer of phosphate group from SpaK to SpaR.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1000401.g003