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Getting Started in Computational Mass Spectrometry–Based Proteomics

Figure 1

Example of spectral data.

(A) LC-MS run. Features in the LC-MS space are peptide ions; their intensity is related to peptide abundance. (B) MS/MS spectrum. The spectrum is obtained by fragmenting the peptide ion isolated from an LC-MS peak. The peaks are fragment ions; distances between peaks are used for peptide sequence determination.

Figure 1

doi: https://doi.org/10.1371/journal.pcbi.1000366.g001