A Dynamic Network Approach for the Study of Human Phenotypes
Figure 3
The Phenotypic Disease Network and disease dynamics.
A. Schematic representation of the three dynamical questions explore here. B. Average φ-correlation between diseases diagnosed in the first two and last two visits for the 946,580 patients with 4 visits (green) and when we consider a randomized set of diseases for the first two visits (red). C. Same as B but for the RR-PDN. D. Ratio between the average φ-correlation among diagnoses received by a patient in its first two and last two visits relative to the control case. E. same as D but for the RR-PDN. F. Gender and race differences. The subset of Fig 2 B where all diseases connected to hypertension and ischemic heart disease is shown. Blue links indicate comorbidities that are strongest among black males; whereas red links indicate comorbidities that are strongest among white males (see legend).