Hypertrophy and/or Hyperplasia: Dynamics of Adipose Tissue Growth
Figure 2
Physiological characteristics of FVB and C57 mice.
(A) Glucose tolerance test was performed on week 10 of controlled feeding with chow and high-fat diet. Mice were fasted overnight and injected with glucose (2 mg/g, i.p.). Each group was represented by 8 mice. (B) Whole body oxidation of oleic acid was measured 10-week old male FVB ad C57 mice in non-fasted state (8 mice per group) as described in Gautam et al. [47]. (C) Oxidation in palmitic acids was measured in soleus muscle dissected from 10-week-old FVB and C57 mice maintained on chow diet (8 mice per group). Samples were collected at 8 am from randomly fed mice or mice fasted for 18 hours [methods in Toyoshima et al. [46]]. (D) Triglyceride clearance in FVB and C57 male mice after 11 weeks of controlled feeding with chow and high fat diet. Mice were fasted for 4 h and then given 400 ยตl of peanut oil by a gavage. Plasma was collected hourly for 5 h from the tail vein for triglyceride measurement. Each group was represented by 8 mice.