Computational Model of the Insect Pheromone Transduction Cascade
Figure 7
Predicted kinetics of the main chemical species, currents and potential at various uptakes.
(A) Activated receptor R*. (B) Effector enzyme E*. (C) Second messengers DAG. (D) Ca2+. Major depolarizing currents (E) Icat and (F) ICl. (G) Major repolarizing current IK. (H) SP. Responses are shown for 2-s square pulses yielding different uptakes regularly spaced by 0.5 log units from 10−4.75 to 101.5 µM/s. Note that the scales of the time axes for DAG concentration (C) and cationic current (E) are not the same as for the other species and currents. Kinetics of IP3 (not shown) is identical to that of DAG (C).