Genome-Scale Reconstruction of Escherichia coli's Transcriptional and Translational Machinery: A Knowledge Base, Its Mathematical Formulation, and Its Functional Characterization
Figure 3
Comparison of in vivo [42] and in silico maximal number of ribosomes at different doubling times.
Two sets of constraints were applied to the models: uptake rates for amino acids and NTPs, and maximal possible rates on stable RNA transcription initiation (see text for more details).